Maternal Floor Infarction Pregnancy

The disease is characterized by extensive fibrin deposition in the intervillous spaces.

Maternal floor infarction pregnancy.

Previously pregnancy associated major basic protein has been localized to the placental x cell and identified at elevated levels in serum and amniotic fluid in all normal pregnancies. Maternal floor infarction of the placenta is characterized by gross placental abnormalities and histologic evidence of x cell proliferation. Maternal floor infarction is a relatively rare condition characterized clinically by severe early onset fetal growth restriction with features of uteroplacental insufficiency. It has a very high recurrence rate and carries a significant risk or fetal demise.

Damage to the decidua basalis by ischemia or infection may initiate many floor infarcts. Maternal floor infarction is a relatively rare condition characterized clinically by severe early onset fetal growth restriction with features of uteroplacental insufficiency. It is also known as massive perivillous fibrin deposition. Thickened fibrin or extravillous matrix at the interface of placenta and basal decidua could produce such an infarction.

Atheroma in the decidual arteries foci of decidual necrosis and histologic evidence of low uteroplacental blood flow were more frequent in patients with floor infarcts. Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe. Previously pregnancy associated major basic protein has been localized to the placental x cell and identified at elevated levels in serum and amniotic fluid in all normal pregnancies. The term infarction is a misnomer because true placental infarcts result from arterial occlusion and ischemic necrosis of the villi.

It has a very high recurrence rate and carries a significant risk or fetal demise. The enveloped villi become atrophic and avascular. Maternal floor infarction is one of the least rec ognized and most poorly understood disorders of pregnancy. Maternal floor infarction then logically should refer to obstruction of blood flow of the arterial entrance to the intervillous space causing necrosis of the overlying placenta.

1 3 the condition has been infrequently discussed in the obstetric or pathology literature and essentially no information is available in pediatric or genetic journals. Maternal floor infarction of the placenta is characterized by gross placental abnormalities and histologic evidence of x cell proliferation. Maternal floor infarction abbreviated mfi is a pathology of the placenta.