Maternal floor infarction of the placenta is a relatively rare disorder that leads to sudden iufd2 incidence.
Maternal floor infarction placenta.
In the 6 cases without placental histologic findings available mfi seemed unlikely because all 6 had normal outcomes.
Maternal floor infarction occurred in 3 11 of these 28 cases.
Previously pregnancy associated major basic protein has been localized to the placental x cell and identified at elevated levels in serum and amniotic fluid in all normal pregnancies.
Of the 28 cases with placental histologic find ings available extensive subchorionic fibrin deposition had been reported in 14 cases 50.
The enveloped villi become atrophic and avascular.
Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe.
Infarction normally refers to occlusion of an end artery to a portion of tissue with subsequent ischemic necrosis death of that tissue most notably occurring in the brain or heart but also in the placenta.
Damage to the decidua basalis by ischemia or infection may initiate many floor infarcts.
To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction mfi of the placenta to gestational age matched controls.
It is also known as massive perivillous fibrin deposition.
Maternal floor infarction frequently recurs in successive pregnancies rate 39 2 and there is evidence that it develops rapidly.
In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed.
Low maternal blood volume may contribute to the low blood flow because maternal hemoglobin values were often abnormally high in gravidas in whom floor infarcts developed.
Atheroma in the decidual arteries foci of decidual necrosis and histologic evidence of low uteroplacental blood flow were more frequent in patients with floor infarcts.
Maternal floor infarction abbreviated mfi is a pathology of the placenta.
The pathophysiology of the lesion remains unclear.
The term infarction is a misnomer because true placental infarcts result from arterial occlusion and ischemic necrosis of the villi.
Maternal floor infarction of the placenta is characterized by gross placental abnormalities and histologic evidence of x cell proliferation.
The disease is characterized by extensive fibrin deposition in the intervillous spaces.
Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence.
