Mat Test For Leptospira

The microscopic agglutination test mat is the basis of serological diagnosis and classification.

Mat test for leptospira.

World organisation for animal health oie 2008. Mat has high sensitivity and detects serovar specific antibodies. Korver department of biomedical research royal tropical institute meibergdreef 39 11005 az amsterdam the netherlands get pdf file. Leptospirosis is diagnosed on clinical grounds and confirmed by microscopic agglutination test mat.

A single elevated mat titer in a patient with a compatible febrile illness and suspected exposure. Microscopic agglutination test mat for the diagnosis of leptospirosis and serotyping of leptospires. Seroconversion with a 4 fold or larger rise in titer between acute and convalescent phase serum specimens obtained 2 weeks or more apart confirms the diagnosis. The microscopic agglutination test mat is the gold standard for sero diagnosis of leptospirosis because of its unsurpassed diagnostic specificity.

A 4 fold rise in mat titer between acute and convalescent sera. It uses panels of live leptospires ideally recent isolates representing the circulating serovars from the area where the patient became infected. Igm elisa serion virion and immunochromatography test leptocheck wb are two immunodiagnostic assays for leptospirosis. The centers for disease control and prevention cdc laboratory in atlanta georgia performs the mat using 23 leptospire antigens.